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Cathepsin B 抗体

This anti-Cathepsin B antibody is a 兔 多克隆 antibody detecting Cathepsin B in IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7234866
发货至: 中国

Quick Overview for Cathepsin B 抗体 (ABIN7234866)

抗原

See all Cathepsin B (CTSB) 抗体
Cathepsin B (CTSB)

适用

  • 64
  • 25
  • 25
  • 7
  • 1
人, 小鼠, 大鼠

宿主

  • 51
  • 18
  • 3
  • 1
  • 1

克隆类型

  • 51
  • 23
多克隆

标记

  • 36
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cathepsin B antibody is un-conjugated

应用范围

  • 53
  • 30
  • 23
  • 18
  • 13
  • 13
  • 13
  • 12
  • 9
  • 5
  • 3
  • 3
Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human CTSB

    亚型

    IgG
  • 应用备注

    IHC 1:150-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.8 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Cathepsin B (CTSB)

    别名

    Cathepsin B

    背景

    The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.

    UniProt

    P07858

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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